Cargando…

Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome

Mitochondrial DNA (mtDNA) leakage into the cytoplasm can occur when cells are exposed to noxious stimuli. Specific sensors recognize cytoplasmic mtDNA to promote cytokine production. Cytoplasmic mtDNA can also be secreted extracellularly, leading to sterile inflammation. However, the mode of secreti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Konaka, Hachiro, Kato, Yasuhiro, Hirano, Toru, Tsujimoto, Kohei, Park, JeongHoon, Koba, Taro, Aoki, Wataru, Matsuzaki, Yusei, Taki, Masayasu, Koyama, Shohei, Itotagawa, Eri, Jo, Tatsunori, Hirayama, Takehiro, Kawai, Taro, Ishii, Ken J, Ueda, Mitsuyoshi, Yamaguchi, Shigehiro, Akira, Shizuo, Morita, Takayoshi, Maeda, Yuichi, Nishide, Masayuki, Nishida, Sumiyuki, Shima, Yoshihito, Narazaki, Masashi, Takamatsu, Hyota, Kumanogoh, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577637/ https://www.ncbi.nlm.nih.gov/pubmed/37661814 http://dx.doi.org/10.15252/embj.2022112573

Ejemplares similares

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis
por: Itotagawa, Eri, et al.
Publicado: (2022)

The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus
por: Kajihara, Akiko, et al.
Publicado: (2022)

The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II
por: Nakatani, Takeshi, et al.
Publicado: (2021)

Apoptosis-derived membrane vesicles drive the cGAS–STING pathway and enhance type I IFN production in systemic lupus erythematosus
por: Kato, Yasuhiro, et al.
Publicado: (2018)

The Ragulator complex: delving its multifunctional impact on metabolism and beyond
por: Tsujimoto, Kohei, et al.
Publicado: (2023)

A case of SAPHO syndrome with the lesions limited to the skull
por: Oguro, Eri, et al.
Publicado: (2020)

Regulation of immune cell responses by semaphorins and their receptors
por: Kumanogoh, Atsushi, et al.
Publicado: (2012)

Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder
por: Murata, Hisashi, et al.
Publicado: (2022)

Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy
por: ITO, TAKUJI, et al.
Publicado: (2014)

Persistence of SARS-CoV-2 neutralizing antibodies and anti-Omicron IgG induced by BNT162b2 mRNA vaccine in patients with autoimmune inflammatory rheumatic disease: an explanatory study in Japan
por: Yamaguchi, Yuta, et al.
Publicado: (2022)

Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis
por: Nishide, Masayuki, et al.
Publicado: (2017)

A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling
por: Briones, Jonathan C., et al.
Publicado: (2020)

LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation
por: Morimoto, Keiko, et al.
Publicado: (2016)

Semaphorin 6D–expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung
por: Naito, Maiko, et al.
Publicado: (2022)

Estrogen-Dependent Proteolytic Cleavage of Semaphorin 4D and Plexin-B1 Enhances Semaphorin 4D-Induced Apoptosis during Postnatal Vaginal Remodeling in Pubescent Mice
por: Ito, Takuji, et al.
Publicado: (2014)

Semaphorin 4D induces vaginal epithelial cell apoptosis to control mouse postnatal vaginal tissue remodeling
por: ITO, TAKUJI, et al.
Publicado: (2015)

Intrinsic Dynamic and Static Nature of π···π Interactions in Fused Benzene-Type Helicenes and Dimers, Elucidated with QTAIM Dual Functional Analysis
por: Nishide, Taro, et al.
Publicado: (2022)

Pulmonary artery hypertension prior to the relapse of adult‐onset Still's disease
por: Hara, Yuki, et al.
Publicado: (2021)

Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology
por: Zhu, Chen, et al.
Publicado: (2020)

Single Cell Analysis of Neutrophils NETs by Microscopic LSPR Imaging System
por: Ahmad Mohamed Ali, Riyaz, et al.
Publicado: (2019)

Late-stage functionalisation of alkyne-modified phospha-xanthene dyes: lysosomal imaging using an off–on–off type of pH probe
por: Ogasawara, Hiroaki, et al.
Publicado: (2021)

Front Cover: Intrinsic Dynamic Nature of Neutral Hydrogen Bonds Elucidated with QTAIM Dual Functional Analysis: Role of the Compliance Force Constants and QTAIM‐DFA Parameters in Stability (ChemistryOpen 8/2018)
por: Nishide, Taro, et al.
Publicado: (2018)

Intrinsic Dynamic Nature of Neutral Hydrogen Bonds Elucidated with QTAIM Dual Functional Analysis: Role of the Compliance Force Constants and QTAIM‐DFA Parameters in Stability
por: Nishide, Taro, et al.
Publicado: (2018)

Intrinsic Dynamic Nature of Neutral Hydrogen Bonds Elucidated with QTAIM Dual Functional Analysis: Role of the Compliance Force Constants and QTAIM‐DFA Parameters in Stability
por: Nishide, Taro, et al.
Publicado: (2018)

Dynamic and Static Nature of Br(4)σ(4c–6e) and Se(2)Br(5)σ(7c–10e) in the Selenanthrene System and Related Species Elucidated by QTAIM Dual Functional Analysis with QC Calculations
por: Hayashi, Satoko, et al.
Publicado: (2020)

Nature of intramolecular O–H⋯π interactions as elucidated by QTAIM dual functional analysis with QC calculations
por: Hayashi, Satoko, et al.
Publicado: (2019)

Intrinsic dynamic and static nature of each HB in the multi-HBs between nucleobase pairs and its behavior, elucidated with QTAIM dual functional analysis and QC calculations
por: Nakanishi, Waro, et al.
Publicado: (2020)

Toll-like receptor downstream signaling
por: Kawai, Taro, et al.
Publicado: (2005)

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins
por: Kawai, Taro, et al.
Publicado: (2011)

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis
por: Nishide, Masayuki, et al.
Publicado: (2023)

572 Effect of Enzymatically Modified Isoquercitrin, a Flavonoid, on Symptoms of Japanese Cedar Pollinosis
por: Tanaka, Toshio, et al.
Publicado: (2012)

Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis
por: Morita, Takayoshi, et al.
Publicado: (2019)

Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity
por: Tsuda, Takeshi, et al.
Publicado: (2018)

PlexinA1-deficient mice exhibit decreased cell density and augmented oxidative stress in parvalbumin-expressing interneurons in the medial prefrontal cortex
por: Jahan, Mst Sharifa, et al.
Publicado: (2022)

Intrinsic Dynamic and Static Nature of Halogen Bonding in Neutral Polybromine Clusters, with the Structural Feature Elucidated by QTAIM Dual-Functional Analysis and MO Calculations
por: Hayashi, Satoko, et al.
Publicado: (2021)

Linear Multiselenium Interactions in Dicationic Oligomers of 1,5‐(Diselena)canes: Behavior of Se(mc) σ(m(c)c‐n(e)e) (6≤m(c)≤16) Elucidated with QTAIM Dual Functional Analysis
por: Hayashi, Satoko, et al.
Publicado: (2021)

Continuous Use of Etanercept During Pregnancy Does Not Affect TNF-Alpha Levels in Umbilical Cord Blood
por: Nishide, Masayuki, et al.
Publicado: (2022)

Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins
por: Tsuchida, Tetsuo, et al.
Publicado: (2009)

A case of Takayasu arteritis complicated with pulmonary infarction
por: Hirayama, Takehiro, et al.
Publicado: (2022)

Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals
por: Kimura, Tetsuya, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ro95h0q02ppmi96frm0qr9n9a7