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Extra centrosomes induce PIDD1‐mediated inflammation and immunosurveillance

Unscheduled increases in ploidy underlie defects in tissue function, premature aging, and malignancy. A concomitant event to polyploidization is the amplification of centrosomes, the main microtubule organization centers in animal cells. Supernumerary centrosomes are frequent in tumors, correlating...

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Detalles Bibliográficos
Autores principales: Garcia‐Carpio, Irmina, Braun, Vincent Z, Weiler, Elias S, Leone, Marina, Niñerola, Sergio, Barco, Angel, Fava, Luca L, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577638/
https://www.ncbi.nlm.nih.gov/pubmed/37530438
http://dx.doi.org/10.15252/embj.2023113510