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Extra centrosomes induce PIDD1‐mediated inflammation and immunosurveillance
Unscheduled increases in ploidy underlie defects in tissue function, premature aging, and malignancy. A concomitant event to polyploidization is the amplification of centrosomes, the main microtubule organization centers in animal cells. Supernumerary centrosomes are frequent in tumors, correlating...
Autores principales: | Garcia‐Carpio, Irmina, Braun, Vincent Z, Weiler, Elias S, Leone, Marina, Niñerola, Sergio, Barco, Angel, Fava, Luca L, Villunger, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577638/ https://www.ncbi.nlm.nih.gov/pubmed/37530438 http://dx.doi.org/10.15252/embj.2023113510 |
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