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Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury

BACKGROUND: Neural stem cells (NSCs) derived from the embryonic spinal cord are excellent candidates for the cellular regeneration of lost neural cells after spinal cord injury (SCI). Semaphorin 3 A (Sema3A) is well known as being implicated in the major axon guidance of the growth cone as a repulsi...

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Detalles Bibliográficos
Autores principales: Kim, Seong Jun, Ko, Wan-Kyu, Han, Gong Ho, Lee, Daye, Cho, Min Jai, Sheen, Seung Hun, Sohn, Seil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577901/
https://www.ncbi.nlm.nih.gov/pubmed/37840145
http://dx.doi.org/10.1186/s40824-023-00434-2