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Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia

BACKGROUND: Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features, is difficult to diagnose and treat. A better characterization of MPAL is essential to understand the subtype heterogeneity and how it compares with...

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Detalles Bibliográficos
Autores principales: Mumme, Hope L., Raikar, Sunil S., Bhasin, Swati S., Thomas, Beena E., Lawrence, Taylor, Weinzierl, Elizabeth P., Pang, Yakun, DeRyckere, Deborah, Gawad, Chuck, Wechsler, Daniel S., Porter, Christopher C., Castellino, Sharon M., Graham, Douglas K., Bhasin, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577904/
https://www.ncbi.nlm.nih.gov/pubmed/37845689
http://dx.doi.org/10.1186/s13073-023-01241-z