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Proteomic analysis of lysine 2-hydroxyisobutyryl in SLE reveals protein modification alteration in complement and coagulation cascades and platelet activation Pathways

BACKGROUND: Post-translational modifications (PTMs) are considered to be an important factor in the pathogenesis of Systemic lupus erythematosus (SLE). Lysine 2-hydroxyisobutyryl (Khib), as an emerging post-translational modification of proteins, is involved in some important biological metabolic ac...

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Detalles Bibliográficos
Autores principales: Kuang, Chaoying, Li, Dandan, Zhou, Xianqing, Lin, Hua, Zhang, Ruohan, Xu, Huixuan, Huang, Shaoying, Tang, Fang, Liu, Fanna, Tang, Donge, Dai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577913/
https://www.ncbi.nlm.nih.gov/pubmed/37845672
http://dx.doi.org/10.1186/s12920-023-01656-y