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Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

BACKGROUND: Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogramming of fibroblasts into CM-like cells, various modifications of that strateg...

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Detalles Bibliográficos
Autores principales: Bachamanda Somesh, Dipthi, Klose, Kristin, Maring, Janita A., Kunkel, Désirée, Jürchott, Karsten, Protze, Stephanie I., Klein, Oliver, Nebrich, Grit, Becker, Matthias, Krüger, Ulrike, Nazari-Shafti, Timo Z., Falk, Volkmar, Kurtz, Andreas, Gossen, Manfred, Stamm, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577947/
https://www.ncbi.nlm.nih.gov/pubmed/37840130
http://dx.doi.org/10.1186/s13287-023-03519-w