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Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus

BACKGROUND: In systemic lupus erythematosus (SLE), autoreactive B cells are thought to develop by-passing immune checkpoints and contribute to its pathogenesis. Toll-like receptor (TLR) 7 and 9 signaling have been implicated in their development and differentiation. Although some B cell subpopulatio...

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Detalles Bibliográficos
Autores principales: Yasaka, Ken, Yamazaki, Tomohide, Sato, Hiroko, Shirai, Tsuyoshi, Cho, Minkwon, Ishida, Koji, Ito, Koyu, Tanaka, Tetsuhiro, Ogasawara, Kouetsu, Harigae, Hideo, Ishii, Tomonori, Fujii, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577954/
https://www.ncbi.nlm.nih.gov/pubmed/37840148
http://dx.doi.org/10.1186/s13075-023-03186-5