A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line

Non-small-cell lung carcinoma (NSCLC) is a type of epithelial lung cancer accounting for about 85% of all lung cancers. In our research, a novel lupene derivative namely acetoxy-lup-5(6), 20(29)-diene (ALUP), as well as two known triterpenes; lupeol (LUP) and betulinic acid (BA) were isolated throug...

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Detalles Bibliográficos
Autores principales: Aborehab, Nora M., Salama, Maha M., Ezzat, Shahira M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577955/
https://www.ncbi.nlm.nih.gov/pubmed/37845669
http://dx.doi.org/10.1186/s12906-023-04201-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577955/
https://www.ncbi.nlm.nih.gov/pubmed/37845669
http://dx.doi.org/10.1186/s12906-023-04201-7

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