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Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality

BACKGROUND: Extracellular vesicles (EV) are considered a cell-free alternative to mesenchymal stromal cell (MSC) therapy. Numerous reports describe the efficacy of EV in conferring immunomodulation and promoting angiogenesis, yet others report these activities to be conveyed in EV-free bioproducts....

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Detalles Bibliográficos
Autores principales: Skovronova, Renata, Scaccia, Eleonora, Calcat-i-Cervera, Sandra, Bussolati, Benedetta, O’Brien, Timothy, Bieback, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577984/
https://www.ncbi.nlm.nih.gov/pubmed/37840135
http://dx.doi.org/10.1186/s12967-023-04602-9