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Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality
BACKGROUND: Extracellular vesicles (EV) are considered a cell-free alternative to mesenchymal stromal cell (MSC) therapy. Numerous reports describe the efficacy of EV in conferring immunomodulation and promoting angiogenesis, yet others report these activities to be conveyed in EV-free bioproducts....
Autores principales: | Skovronova, Renata, Scaccia, Eleonora, Calcat-i-Cervera, Sandra, Bussolati, Benedetta, O’Brien, Timothy, Bieback, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577984/ https://www.ncbi.nlm.nih.gov/pubmed/37840135 http://dx.doi.org/10.1186/s12967-023-04602-9 |
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