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Personalized radiomics signature to screen for KIT-11 mutation genotypes among patients with gastrointestinal stromal tumors: a retrospective multicenter study

OBJECTIVES: Gastrointestinal stromal tumors (GISTs) carrying different KIT exon 11 (KIT-11) mutations exhibit varying prognoses and responses to Imatinib. Herein, we aimed to determine whether computed tomography (CT) radiomics can accurately stratify KIT-11 mutation genotypes to benefit Imatinib th...

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Detalles Bibliográficos
Autores principales: Zhang, Qing-Wei, Zhang, Ran-Ying, Yan, Zhi-Bo, Zhao, Yu-Xuan, Wang, Xin-Yuan, Jin, Jing-Zheng, Qiu, Qi-Xuan, Chen, Jie-Jun, Xie, Zhen-Hui, Lin, Jiang, Cao, Hui, Zhou, Yan, Chen, Hui-Min, Li, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577986/
https://www.ncbi.nlm.nih.gov/pubmed/37845765
http://dx.doi.org/10.1186/s12967-023-04520-w