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Antimicrobial peptides modulate lung injury by altering the intestinal microbiota

BACKGROUND: Mammalian mucosal barriers secrete antimicrobial peptides (AMPs) as critical, host-derived regulators of the microbiota. However, mechanisms that support microbiota homeostasis in response to inflammatory stimuli, such as supraphysiologic oxygen, remain unclear. RESULTS: We show that sup...

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Detalles Bibliográficos
Autores principales: Abdelgawad, Ahmed, Nicola, Teodora, Martin, Isaac, Halloran, Brian A., Tanaka, Kosuke, Adegboye, Comfort Y., Jain, Pankaj, Ren, Changchun, Lal, Charitharth V., Ambalavanan, Namasivayam, O’Connell, Amy E., Jilling, Tamás, Willis, Kent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578018/
https://www.ncbi.nlm.nih.gov/pubmed/37845716
http://dx.doi.org/10.1186/s40168-023-01673-0