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Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis

Over the past 30 years, the majority of (pre)clinical efforts to find an effective therapy for Alzheimer’s disease (AD) focused on clearing the β-amyloid peptide (Aβ) from the brain since, according to the amyloid cascade hypothesis, the peptide was (and it is still considered by many) the pathogeni...

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Detalles Bibliográficos
Autor principal: Fedele, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578107/
https://www.ncbi.nlm.nih.gov/pubmed/37833948
http://dx.doi.org/10.3390/ijms241914499