Structural features of thyroglobulin linked to protein trafficking

Thyroglobulin must pass endoplasmic reticulum (ER) quality control to become secreted for thyroid hormone synthesis. Defective thyroglobulin, blocked in trafficking, can cause hypothyroidism. Thyroglobulin is a large protein (~2750 residues) spanning regions I–II–III plus a C‐terminal cholinesterase...

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Detalles Bibliográficos
Autores principales: Citterio, Cintia E., Kim, Kookjoo, Rajesh, Bhavana, Pena, Kevin, Clarke, Oliver Biggs, Arvan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578121/
https://www.ncbi.nlm.nih.gov/pubmed/37717261
http://dx.doi.org/10.1002/pro.4784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578121/
https://www.ncbi.nlm.nih.gov/pubmed/37717261
http://dx.doi.org/10.1002/pro.4784

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