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Structural features of thyroglobulin linked to protein trafficking
Thyroglobulin must pass endoplasmic reticulum (ER) quality control to become secreted for thyroid hormone synthesis. Defective thyroglobulin, blocked in trafficking, can cause hypothyroidism. Thyroglobulin is a large protein (~2750 residues) spanning regions I–II–III plus a C‐terminal cholinesterase...
Autores principales: | Citterio, Cintia E., Kim, Kookjoo, Rajesh, Bhavana, Pena, Kevin, Clarke, Oliver Biggs, Arvan, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578121/ https://www.ncbi.nlm.nih.gov/pubmed/37717261 http://dx.doi.org/10.1002/pro.4784 |
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