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Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro

The pancreatic β cell synthesizes, packages, and secretes insulin in response to glucose-stimulation to maintain blood glucose homeostasis. Under diabetic conditions, a subset of β cells fail and lose expression of key transcription factors (TFs) required for insulin secretion. Among these TFs is Pa...

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Detalles Bibliográficos
Autores principales: Kanojia, Sukrati, Davidson, Rebecca K., Conley, Jason M., Xu, Jerry, Osmulski, Meredith, Sims, Emily K., Ren, Hongxia, Spaeth, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578191/
https://www.ncbi.nlm.nih.gov/pubmed/37838950
http://dx.doi.org/10.1080/19382014.2023.2267725