Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer’s Disease Mouse Model with Humanized TNF Receptor 2

BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is a master cytokine involved in a variety of inflammatory and neurological diseases, including Alzheimer’s disease (AD). Therapies that block TNF-α proved ineffective as therapeutic for neurodegenerative diseases, which might be explained by the oppos...

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Detalles Bibliográficos
Autores principales: Ortí-Casañ, Natalia, Wajant, Harald, Kuiperij, H. Bea, Hooijsma, Annelien, Tromp, Leon, Poortman, Isabelle L., Tadema, Norick, de Lange, Julia H.E., Verbeek, Marcel M., De Deyn, Peter P., Naudé, Petrus J.W., Eisel, Ulrich L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578215/
https://www.ncbi.nlm.nih.gov/pubmed/37355890
http://dx.doi.org/10.3233/JAD-221230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578215/
https://www.ncbi.nlm.nih.gov/pubmed/37355890
http://dx.doi.org/10.3233/JAD-221230

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