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Timing of Alzheimer’s Disease by Intellectual Disability Level in Down Syndrome

BACKGROUND: Trisomy 21 causes Down syndrome (DS) and is a recognized cause of early-onset Alzheimer’s disease (AD). OBJECTIVE: The current study sought to determine if premorbid intellectual disability level (ID) was associated with variability in age-trajectories of AD biomarkers and cognitive impa...

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Detalles Bibliográficos
Autores principales: Hartley, Sigan L., Fleming, Victoria, Schworer, Emily K., Peven, Jamie, Handen, Benjamin L., Krinsky-McHale, Sharon, Hom, Christy, Lee, Laisze, Tudorascu, Dana L., Laymon, Charles, Minhas, Davneet, Luo, Weiquan, Cohen, Annie, Zaman, Shahid, Ances, Beau M., Mapstone, Mark, Head, Elizabeth, Lai, Florence, Rosas, H. Diana, Klunk, William, Christian, Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578224/
https://www.ncbi.nlm.nih.gov/pubmed/37482997
http://dx.doi.org/10.3233/JAD-230200