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ABA Supplementation Rescues IRS2 and BDNF mRNA Levels in a Triple-Transgenic Mice Model of Alzheimer’s Disease

Insulin resistance underlies Alzheimer’s disease (AD) by affecting neuroinflammation and brain-derived neurotrophic factor (BDNF) expression. Here, we evaluated the effect of early and late-start abscisic acid (ABA) intervention on hippocampal BDNF, tumor necrosis factor α (TNFα), and insulin recept...

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Detalles Bibliográficos
Autores principales: Alves-Borba, Laryssa, Espinosa-Fernández, Verónica, Canseco-Rodríguez, Ania, Sánchez-Pérez, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578322/
https://www.ncbi.nlm.nih.gov/pubmed/37849638
http://dx.doi.org/10.3233/ADR-230056