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Endotype Characterization Reveals Mechanistic Differences Across Brain Regions in Sporadic Alzheimer’s Disease

BACKGROUND: While Alzheimer’s disease (AD) pathology is associated with altered brain structure, it is not clear whether gene expression changes mirror the onset and evolution of pathology in distinct brain regions. Deciphering the mechanisms which cause the differential manifestation of the disease...

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Detalles Bibliográficos
Autores principales: Patel, Ashay O., Caldwell, Andrew B., Ramachandran, Srinivasan, Subramaniam, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578327/
https://www.ncbi.nlm.nih.gov/pubmed/37849634
http://dx.doi.org/10.3233/ADR-220098