Morphine-induced osteolysis and hypersensitivity is mediated through toll-like receptor-4 in a murine model of metastatic breast cancer

The propensity for breast cancer to metastasize to bone is coupled to the most common complaint among breast cancer patients: bone pain. Classically, this type of pain is treated using escalating doses of opioids, which lack long-term efficacy due to analgesic tolerance, opioid-induced hypersensitiv...

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Detalles Bibliográficos
Autores principales: Thompson, Austen L., Grenald, Shaness A., Ciccone, Haley A., Mohty, Dieter, Smith, Angela F., Coleman, Deziree L., Bahramnejad, Erfan, De Leon, Erick, Kasper-Conella, Logan, Uhrlab, Jennifer L., Margolis, David S., Salvemini, Daniela, Largent-Milnes, Tally M., Vanderah, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578422/
https://www.ncbi.nlm.nih.gov/pubmed/37326644
http://dx.doi.org/10.1097/j.pain.0000000000002953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578422/
https://www.ncbi.nlm.nih.gov/pubmed/37326644
http://dx.doi.org/10.1097/j.pain.0000000000002953

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