Cargando…
Discovering pathways through ribozyme fitness landscapes using information theoretic quantification of epistasis
The identification of catalytic RNAs is typically achieved through primarily experimental means. However, only a small fraction of sequence space can be analyzed even with high-throughput techniques. Methods to extrapolate from a limited data set to predict additional ribozyme sequences, particularl...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578471/ https://www.ncbi.nlm.nih.gov/pubmed/37580126 http://dx.doi.org/10.1261/rna.079541.122 |