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HBV suppresses macrophage immune responses by impairing the TCA cycle through the induction of CS/PDHC hyperacetylation

BACKGROUND: It is now understood that HBV can induce innate and adaptive immune response disorders by affecting immunosuppressive macrophages, resulting in chronic HBV infection. However, the underlying mechanism is not fully understood. Dysregulated protein acetylation can reportedly influence the...

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Detalles Bibliográficos
Autores principales: Bei, Jiaxin, Chen, Ye, Zhang, Qianbing, Wang, Xiaobin, Lin, Liteng, Huang, Jingjun, Huang, Wensou, Cai, Mingyue, Cai, Weiguo, Guo, Yongjian, Zhu, Kangshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578720/
https://www.ncbi.nlm.nih.gov/pubmed/37820280
http://dx.doi.org/10.1097/HC9.0000000000000294