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sTREM2 is a plasma biomarker for human NASH and promotes hepatocyte lipid accumulation

BACKGROUND: Pathogenetic mechanisms of the progression of NAFL to advanced NASH coupled with potential noninvasive biomarkers and novel therapeutic targets are active areas of investigation. The recent finding that increased plasma levels of a protein shed by myeloid cells —soluble Triggering Recept...

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Detalles Bibliográficos
Autores principales: Kothari, Vishal, Savard, Christopher, Tang, Jingjing, Lee, Sum P., Subramanian, Savitha, Wang, Shari, den Hartigh, Laura J., Bornfeldt, Karin E., Ioannou, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578746/
https://www.ncbi.nlm.nih.gov/pubmed/37820278
http://dx.doi.org/10.1097/HC9.0000000000000265