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Tissue-specific differences in the assembly of mitochondrial Complex I are revealed by a novel ENU mutation in ECSIT

AIMS: Mitochondrial Complex I assembly (MCIA) is a multi-step process that necessitates the involvement of a variety of assembly factors and chaperones to ensure that the final active enzyme is correctly assembled. The role of the assembly factor evolutionarily conserved signalling intermediate in t...

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Detalles Bibliográficos
Autores principales: Nicol, Thomas, Falcone, Sara, Blease, Andrew, Vikhe, Pratik, Civiletto, Gabriele, Omairi, Saleh Salman, Viscomi, Carlo, Patel, Ketan, Potter, Paul K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578914/
https://www.ncbi.nlm.nih.gov/pubmed/37395010
http://dx.doi.org/10.1093/cvr/cvad101