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Unbiased gene expression analysis of the delayed fracture healing observed in Zucker diabetic fatty rats

AIMS: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to compare GE in the fracture callus of Zucker di...

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Detalles Bibliográficos
Autores principales: Sung, Jonghoo, Barratt, Kate R., Pederson, Stephen M., Chenu, Chantal, Reichert, Ines, Atkins, Gerald J., Anderson, Paul H., Smitham, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578971/
https://www.ncbi.nlm.nih.gov/pubmed/37844909
http://dx.doi.org/10.1302/2046-3758.1210.BJR-2023-0062.R1