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橙皮素通过激活SIRT1/NRF2信号改善阿霉素诱导的H9c2细胞毒性

OBJECTIVE: To investigate whether hesperetin (Hes) alleviates doxorubicin (DOX)-induced cardiomyocytotoxicity by reducing oxidative stress via regulating silent information regulator 1 (SIRT1)/nuclear transcription factor E2-related factor 2 (NRF2) signaling in H9c2 cells. METHODS: H9c2 cells were t...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 四川大学学报(医学版)编辑部 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579077/
https://www.ncbi.nlm.nih.gov/pubmed/37866951
http://dx.doi.org/10.12182/20230960207