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Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women

Fatty liver disease (FLD) caused by metabolic dysfunction is the leading cause of liver disease and the prevalence is rising, especially in women. Although during reproductive age women are protected against FLD, for still unknown and understudied reasons some develop rapidly progressive disease at...

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Detalles Bibliográficos
Autores principales: Cherubini, Alessandro, Ostadreza, Mahnoosh, Jamialahmadi, Oveis, Pelusi, Serena, Rrapaj, Eniada, Casirati, Elia, Passignani, Giulia, Norouziesfahani, Marjan, Sinopoli, Elena, Baselli, Guido, Meda, Clara, Dongiovanni, Paola, Dondossola, Daniele, Youngson, Neil, Tourna, Aikaterini, Chokshi, Shilpa, Bugianesi, Elisabetta, Della Torre, Sara, Prati, Daniele, Romeo, Stefano, Valenti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579099/
https://www.ncbi.nlm.nih.gov/pubmed/37749332
http://dx.doi.org/10.1038/s41591-023-02553-8