The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk

Cytotoxic lymphocytes eliminate cancer cells through the release of lytic granules, a specialized form of secretory lysosomes. This compartment is part of the pleomorphic endolysosomal system and is distinguished by its highly dynamic Ca(2+) signaling machinery. Several transient receptor potential...

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Detalles Bibliográficos
Autores principales: Clement, Dennis, Szabo, Edina K., Krokeide, Silje Zandstra, Wiiger, Merete Thune, Vincenti, Marianna, Palacios, Daniel, Chang, Young-Tae, Grimm, Christian, Patel, Sandip, Stenmark, Harald, Brech, Andreas, Majhi, Rakesh Kumar, Malmberg, Karl-Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Immune Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579149/
https://www.ncbi.nlm.nih.gov/pubmed/37737664
http://dx.doi.org/10.4049/jimmunol.2300406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579149/
https://www.ncbi.nlm.nih.gov/pubmed/37737664
http://dx.doi.org/10.4049/jimmunol.2300406

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