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Experimental and modeling of solubility of sitagliptin phosphate, in supercritical carbon dioxide: proposing a new association model
The solubility of an anti-hyperglycemic agent drug, (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4] triazolo[4,3-a] pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-amine (also known as Sitagliptin phosphate) in supercritical carbon dioxide (scCO(2)) was determined by ananalytical and dynami...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579220/ https://www.ncbi.nlm.nih.gov/pubmed/37845347 http://dx.doi.org/10.1038/s41598-023-44787-z |