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Experimental and modeling of solubility of sitagliptin phosphate, in supercritical carbon dioxide: proposing a new association model

The solubility of an anti-hyperglycemic agent drug, (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4] triazolo[4,3-a] pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-amine (also known as Sitagliptin phosphate) in supercritical carbon dioxide (scCO(2)) was determined by ananalytical and dynami...

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Detalles Bibliográficos
Autores principales:	Ardestani, Nedasadat Saadati, Sajadian, Seyed Ali, Esfandiari, Nadia, Rojas, Adrián, Garlapati, Chandrasekhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579220/ https://www.ncbi.nlm.nih.gov/pubmed/37845347 http://dx.doi.org/10.1038/s41598-023-44787-z

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