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Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs
In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and druggability were tested in vitro and in silico, respectively, observing as a result: firstly, compounds sh...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579228/ https://www.ncbi.nlm.nih.gov/pubmed/37845281 http://dx.doi.org/10.1038/s41598-023-43805-4 |