Cargando…
Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs
In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and druggability were tested in vitro and in silico, respectively, observing as a result: firstly, compounds sh...
Autores principales: | Espinosa-Saez, Roger, Robledo, Sara M., Pineda, Tatiana, Murillo, Javier, Zúñiga, César, Yañez, Osvaldo, Cantero-López, Plinio, Saez-Vega, Alex, Guzmán-Teran, Camilo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579228/ https://www.ncbi.nlm.nih.gov/pubmed/37845281 http://dx.doi.org/10.1038/s41598-023-43805-4 |
Ejemplares similares
-
Antileishmanial activity of synthetic analogs of the naturally occurring quinolone alkaloid N-methyl-8-methoxyflindersin
por: Torres Suarez, Elaine, et al.
Publicado: (2020) -
Study of the in Vitro Antiplasmodial, Antileishmanial and Antitrypanosomal Activities of Medicinal Plants from Saudi Arabia
por: Al-Musayeib, Nawal M., et al.
Publicado: (2012) -
Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root of Antrocaryon klaineanum Pierre (Anacardiaceae)
por: Amang à Ngnoung, Gabrielle Ange, et al.
Publicado: (2023) -
Antileishmanial Effects of Synthetic EhPIb Analogs Derived from the Entamoeba histolytica Lipopeptidephosphoglycan
por: Fehling, Helena, et al.
Publicado: (2020) -
Organocatalytic atroposelective heterocycloaddition to access axially chiral 2-arylquinolines
por: Yang, Gongming, et al.
Publicado: (2021)