A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity

Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus undergoes epochal evolution with periodic emergence of variants with new anti...

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Detalles Bibliográficos
Autores principales: Salmen, Wilhelm, Hu, Liya, Bok, Marina, Chaimongkol, Natthawan, Ettayebi, Khalil, Sosnovtsev, Stanislav V., Soni, Kaundal, Ayyar, B. Vijayalakshmi, Shanker, Sreejesh, Neill, Frederick H., Sankaran, Banumathi, Atmar, Robert L., Estes, Mary K., Green, Kim Y., Parreño, Viviana, Prasad, B. V. Venkataram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579229/
https://www.ncbi.nlm.nih.gov/pubmed/37845211
http://dx.doi.org/10.1038/s41467-023-42146-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579229/
https://www.ncbi.nlm.nih.gov/pubmed/37845211
http://dx.doi.org/10.1038/s41467-023-42146-0

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