Unexpected gender differences in progressive supranuclear palsy reveal efficacy for davunetide in women

Progressive supranuclear palsy (PSP) is a pure tauopathy, implicating davunetide, enhancing Tau-microtubule interaction, as an ideal drug candidate. However, pooling patient data irrespective of sex concluded no efficacy. Here, analyzing sex-dependency in a 52 week-long- PSP clinical trial (involvin...

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Detalles Bibliográficos
Autores principales: Gozes, Illana, Shapira, Guy, Lobyntseva, Alexandra, Shomron, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579238/
https://www.ncbi.nlm.nih.gov/pubmed/37845254
http://dx.doi.org/10.1038/s41398-023-02618-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579238/
https://www.ncbi.nlm.nih.gov/pubmed/37845254
http://dx.doi.org/10.1038/s41398-023-02618-9

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