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A human lung alveolus-on-a-chip model of acute radiation-induced lung injury

Acute exposure to high-dose gamma radiation due to radiological disasters or cancer radiotherapy can result in radiation-induced lung injury (RILI), characterized by acute pneumonitis and subsequent lung fibrosis. A microfluidic organ-on-a-chip lined by human lung alveolar epithelium interfaced with...

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Detalles Bibliográficos
Autores principales: Dasgupta, Queeny, Jiang, Amanda, Wen, Amy M., Mannix, Robert J., Man, Yuncheng, Hall, Sean, Javorsky, Emilia, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579267/
https://www.ncbi.nlm.nih.gov/pubmed/37845224
http://dx.doi.org/10.1038/s41467-023-42171-z