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Progress in understanding the role of cGAS-STING pathway associated with programmed cell death in intervertebral disc degeneration
Nucleus pulposus (NP) inflammatory response can induce intervertebral disc degeneration (IVDD) by causing anabolic and catabolic disequilibrium of the extracellular matrix (ECM). This process is accompanied by the production of endogenous DNAs, then detectable by the DNA sensor cyclic GMP-AMP syntha...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579269/ https://www.ncbi.nlm.nih.gov/pubmed/37845198 http://dx.doi.org/10.1038/s41420-023-01607-7 |