Progress in understanding the role of cGAS-STING pathway associated with programmed cell death in intervertebral disc degeneration

Nucleus pulposus (NP) inflammatory response can induce intervertebral disc degeneration (IVDD) by causing anabolic and catabolic disequilibrium of the extracellular matrix (ECM). This process is accompanied by the production of endogenous DNAs, then detectable by the DNA sensor cyclic GMP-AMP syntha...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Hu, Xinli, Cui, Peng, Kong, Chao, Chen, Xiaolong, Wang, Wei, Lu, Shibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579269/
https://www.ncbi.nlm.nih.gov/pubmed/37845198
http://dx.doi.org/10.1038/s41420-023-01607-7

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