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Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood

Glutamatergic NMDA receptors (NMDAR) are critical for cognitive function, and their reduced expression leads to intellectual disability. Since subpopulations of NMDARs exist in distinct subcellular environments, their functioning may be unevenly vulnerable to genetic disruption. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Venkatesan, Sridevi, Binko, Mary A., Mielnik, Catharine A., Ramsey, Amy J., Lambe, Evelyn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579298/
https://www.ncbi.nlm.nih.gov/pubmed/37349472
http://dx.doi.org/10.1038/s41386-023-01619-y