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LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines

Leukocyte-associated immunoglobulin-like receptor-1 (LAIR1), an immune receptor containing immunoreceptor tyrosine-based inhibiory motifs (ITIMs), has emerged as an attractive target for cancer therapy. However, the intrinsic function of LAIR1 in gliomas remains unclear. In this study, the poor prog...

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Detalles Bibliográficos
Autores principales: Wei, Xiaoqian, Pan, Shushan, Wang, Zirui, Chen, Jieru, Lu, Li, Cao, Qizhi, Song, Shuling, Zhang, Huachang, Liu, Xiaohui, Qu, Xianjun, Lin, Xiukun, Xu, Huanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579300/
https://www.ncbi.nlm.nih.gov/pubmed/37845206
http://dx.doi.org/10.1038/s41419-023-06199-9