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Impact of transient acquired hypermutability on the inter- and intra-species competitiveness of Pseudomonas aeruginosa

Once acquired, hypermutation is unrelenting, and in the long-term, leads to impaired fitness due to its cumulative impact on the genome. This raises the question of why hypermutators arise so frequently in microbial ecosystems. In this work, we explore this problem by examining how the transient acq...

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Detalles Bibliográficos
Autores principales: On, Yue Yuan, Figueroa, Wendy, Fan, Catherine, Ho, Pok-Man, Bényei, Éva Bernadett, Weimann, Aaron, Ruis, Christopher, Floto, Andres R., Welch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579334/
https://www.ncbi.nlm.nih.gov/pubmed/37666975
http://dx.doi.org/10.1038/s41396-023-01503-z