Regulatory fine-tuning of mcr-1 increases bacterial fitness and stabilises antibiotic resistance in agricultural settings

Antibiotic resistance tends to carry fitness costs, making it difficult to understand how resistance can be maintained in the absence of continual antibiotic exposure. Here we investigate this problem in the context of mcr-1, a globally disseminated gene that confers resistance to colistin, an agric...

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Detalles Bibliográficos
Autores principales: Ogunlana, Lois, Kaur, Divjot, Shaw, Liam P., Jangir, Pramod, Walsh, Timothy, Uphoff, Stephan, MacLean, R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579358/
https://www.ncbi.nlm.nih.gov/pubmed/37723338
http://dx.doi.org/10.1038/s41396-023-01509-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579358/
https://www.ncbi.nlm.nih.gov/pubmed/37723338
http://dx.doi.org/10.1038/s41396-023-01509-7

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