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Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development

Chronic inflammation promotes development and progression of colorectal cancer (CRC). To comprehensively understand the molecular mechanisms underlying the development and progression of inflamed CRC, we perform in vivo screening and identify 142 genes that are frequently mutated in inflammation-ass...

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Detalles Bibliográficos
Autores principales: Shimomura, Kana, Hattori, Naoko, Iida, Naoko, Muranaka, Yukari, Sato, Kotomi, Shiraishi, Yuichi, Arai, Yasuhito, Hama, Natsuko, Shibata, Tatsuhiro, Narushima, Daichi, Kato, Mamoru, Takamaru, Hiroyuki, Okamoto, Koji, Takeda, Haruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579371/
https://www.ncbi.nlm.nih.gov/pubmed/37845228
http://dx.doi.org/10.1038/s41467-023-42228-z