Cargando…

MafB regulates NLRP3 inflammasome activation by sustaining p62 expression in macrophages

Activation of the NLRP3 inflammasome is a two-step process: the priming and the activating. The priming step involves the induction of NLRP3 and pro-IL-1β, while the activating step leads to the full inflammasome activation triggered by a NLRP3 activator. Although mechanisms underlying the NLRP3 inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Huachun, Banerjee, Sami, Xie, Na, Dey, Tapan, Liu, Rui-Ming, Sanders, Yan Y., Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579372/
https://www.ncbi.nlm.nih.gov/pubmed/37845329
http://dx.doi.org/10.1038/s42003-023-05426-5