IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells

IL-3 has been reported to be involved in various inflammatory disorders, but its role in inflammatory bowel disease (IBD) has not been addressed so far. Here, we determined IL-3 expression in samples from patients with IBD and studied the impact of Il3 or Il3r deficiency on T cell-dependent experime...

Descripción completa

Detalles Bibliográficos
Autores principales: Ullrich, Karen Anne-Marie, Derdau, Julia, Baltes, Carsten, Battistella, Alice, Rosso, Gonzalo, Uderhardt, Stefan, Schulze, Lisa Lou, Liu, Li-Juan, Dedden, Mark, Spocinska, Marta, Kainka, Lucina, Kubánková, Markéta, Müller, Tanja Martina, Schmidt, Nina-Maria, Becker, Emily, Ben Brahim, Oumaima, Atreya, Imke, Finotto, Susetta, Prots, Iryna, Wirtz, Stefan, Weigmann, Benno, López-Posadas, Rocío, Atreya, Raja, Ekici, Arif Bülent, Lautenschläger, Franziska, Guck, Jochen, Neurath, Markus F, Zundler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579496/
https://www.ncbi.nlm.nih.gov/pubmed/37541770
http://dx.doi.org/10.1136/gutjnl-2023-329818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579496/
https://www.ncbi.nlm.nih.gov/pubmed/37541770
http://dx.doi.org/10.1136/gutjnl-2023-329818

Ejemplares similares