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Molecular regulatory mechanism of human myosin-7a

Myosin-7a is an actin-based motor protein essential for vision and hearing. Mutations of myosin-7a cause type 1 Usher syndrome, the most common and severe form of deafblindness in humans. The molecular mechanisms that govern its mechanochemistry remain poorly understood, primarily because of the dif...

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Detalles Bibliográficos
Autores principales: Holló, Alexandra, Billington, Neil, Takagi, Yasuharu, Kengyel, András, Sellers, James R., Liu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579538/
https://www.ncbi.nlm.nih.gov/pubmed/37690683
http://dx.doi.org/10.1016/j.jbc.2023.105243