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Prediction of severe CRS and determination of biomarkers in B cell-acute lymphoblastic leukemia treated with CAR-T cells

INTRODUCTION: CAR-T cell therapy is a novel approach in the treatment of hematological tumors. However, it is associated with life-threatening side effects, such as the severe cytokine release syndrome (sCRS). Therefore, predicting the occurrence and development of sCRS is of great significance for...

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Detalles Bibliográficos
Autores principales: Wei, Zhenyu, Xu, Jiayu, Zhao, Chengkui, Zhang, Min, Xu, Nan, Kang, Liqing, Lou, Xiaoyan, Yu, Lei, Feng, Weixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579557/
https://www.ncbi.nlm.nih.gov/pubmed/37854590
http://dx.doi.org/10.3389/fimmu.2023.1273507