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Mechanism of action of sprG1-encoded type I toxins in Staphylococcus aureus: from membrane alterations to mesosome-like structures formation and bacterial lysis

sprG1/SprF1 is a type I toxin-antitoxin system located on Staphylococcus aureus prophage. It has previously been shown that the two toxins, SprG1(31) and SprG1(44), encoded by the sprG1 gene, are two membrane-associated peptides structured in a single α-helix. Overexpression of these two peptides le...

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Detalles Bibliográficos
Autores principales: Fermon, Laurence, Burel, Agnès, Ostyn, Emeline, Dréano, Stéphane, Bondon, Arnaud, Chevance, Soizic, Pinel-Marie, Marie-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579593/
https://www.ncbi.nlm.nih.gov/pubmed/37854335
http://dx.doi.org/10.3389/fmicb.2023.1275849