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Mechanism of action of sprG1-encoded type I toxins in Staphylococcus aureus: from membrane alterations to mesosome-like structures formation and bacterial lysis
sprG1/SprF1 is a type I toxin-antitoxin system located on Staphylococcus aureus prophage. It has previously been shown that the two toxins, SprG1(31) and SprG1(44), encoded by the sprG1 gene, are two membrane-associated peptides structured in a single α-helix. Overexpression of these two peptides le...
Autores principales: | Fermon, Laurence, Burel, Agnès, Ostyn, Emeline, Dréano, Stéphane, Bondon, Arnaud, Chevance, Soizic, Pinel-Marie, Marie-Laure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579593/ https://www.ncbi.nlm.nih.gov/pubmed/37854335 http://dx.doi.org/10.3389/fmicb.2023.1275849 |
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